Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773642 | 1.00 | HCAR2 (0.57) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL11746166 | 0.87 | HCAR2 (0.59) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL6448412 | 0.87 | HCAR2 (0.59) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL6448405 | 0.87 | HCAR2 (0.59) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL9719196 | 0.85 | HCAR2 (0.52) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL9347791 | 0.85 | HCAR2 (0.52) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL9773737 | 0.84 | HCAR2 (0.55) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL9576267 | 0.83 | HCAR2 (0.50) | HCAR2TSHRACHEBACE1 | |
| SCHEMBL451816 | 0.79 | HCAR2 (0.63) | HCAR2ALDH1A1GAATSHRTP53 | |
| SCHEMBL769452 | 0.79 | HCAR2 (0.57) | HCAR2ALDH1A1GAATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219884-B1 | HARD CONTACT LENS MATERIAL | Tomei Sangyo Kabushiki Kaisha (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0219884-A2 | Hard contact lens material | Tomei Sangyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |