Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 12/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719220 | 0.93 | TSHR (0.44) | HCAR2TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL9576238 | 0.84 | HCAR2 (0.50) | HCAR2TSHRALDH1A1HPGDGAA | |
| SCHEMBL8459106 | 0.84 | HCAR2 (0.56) | HCAR2TSHRLMNATDP1ATM | |
| SCHEMBL15794290 | 0.83 | HCAR2 (0.56) | HCAR2TSHRTDP1ALDH1A1GAA | |
| SCHEMBL15794287 | 0.83 | HCAR2 (0.56) | HCAR2TSHRTDP1ALDH1A1GAA | |
| SCHEMBL28350819 | 0.82 | HCAR2 (0.47) | HCAR2TSHRALDH1A1HPGDATM | |
| SCHEMBL10396417 | 0.82 | HCAR2 (0.47) | HCAR2TSHRALDH1A1HPGDATM | |
| SCHEMBL8461085 | 0.81 | HCAR2 (0.59) | HCAR2TSHRTDP1ATMCYP3A4 | |
| SCHEMBL11236562 | 0.81 | HCAR2 (0.59) | HCAR2TSHRTDP1ATMCYP3A4 | |
| SCHEMBL2021411 | 0.81 | HCAR2 (0.59) | HCAR2TSHRALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |