Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719223 | 0.93 | HCAR2 (0.48) | TSHRHCAR2TDP1LMNAATM | |
| SCHEMBL29054539 | 0.85 | TSHR (0.66) | TSHRTDP1ALDH1A1HPGDUSP2 | |
| SCHEMBL9576303 | 0.82 | ATM (0.47) | TSHRHCAR2TDP1LMNAATM | |
| SCHEMBL8327241 | 0.82 | ATM (0.47) | TSHRHCAR2TDP1LMNAATM | |
| SCHEMBL9576235 | 0.82 | TSHR (0.45) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL31552895 | 0.78 | TSHR (0.42) | TSHRHCAR2TDP1LMNAATM | |
| SCHEMBL8461082 | 0.78 | ATM (0.53) | TSHRHCAR2TDP1LMNAATM | |
| SCHEMBL9576359 | 0.78 | ATM (0.53) | TSHRHCAR2TDP1LMNAATM | |
| SCHEMBL317107 | 0.78 | TSHR (0.67) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL429885 | 0.78 | TSHR (0.67) | TSHRHCAR2ATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |