Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.53 |
| ▸ | MAOB | P27338 | 14/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719137 | 0.98 | MAOA (0.52) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL9719158 | 0.97 | MAOA (0.51) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL9719135 | 0.97 | MAOA (0.51) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL9719202 | 0.97 | MAOA (0.51) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL9719106 | 0.97 | MAOA (0.51) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL9719130 | 0.97 | MAOA (0.51) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL10944049 | 0.91 | MAOA (0.54) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL10947401 | 0.90 | MAOA (0.53) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL10948467 | 0.90 | MAOA (0.53) | MAOAMAOBPABPC1CASP7CASP6 | |
| SCHEMBL10946825 | 0.90 | MAOA (0.53) | MAOAMAOBPABPC1CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104885-A | 5-(phenylalkoxy)primaquine and 5[(heterocycle)alkoxy] primaquine compounds and their use for treatment of malaria | CALSPAN CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |
| US-4980360-A | NONTOXIC AT HIGHER DOSAGES | CALSPAN CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |