SCHEMBL9719308

SCHEMBL9719308

Cc1c2c(cc3c1OC(C)(C)O3)OC(C)(C)O2

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.62
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930662 0.78 TSHR (0.59) TSHRCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL7519328 0.78 TSHR (1.00) TSHRCYP1A2CYP2C9CYP2C19
SCHEMBL15984236 0.76 TSHR (0.50) TSHRCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL8930686 0.76 TSHR (0.56) TSHRCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL13138789 0.75 TSHR (0.42) TSHRALDH1A1
SCHEMBL8930707 0.73 TSHR (0.52) TSHRCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL8930700 0.73 TSHR (0.52) TSHRCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL9719293 0.73 TSHR (0.52) TSHRCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL8930663 0.73 TSHR (0.52) TSHRCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL14337784 0.72 TSHR (0.44) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0515458-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI. HAFSLUND NYCOMED INNOVATION (SE) 1992-12-02 EP disclosed
WO-1991012024-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI HAFSLUND NYCOMED INNOVATION AB (SE) 1991-08-22 WO disclosed