Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248829 | 0.99 | SIGMAR1 (0.38) | SIGMAR1GRIA1GRIA2GRIA3KMT2A | |
| SCHEMBL8045991 | 0.82 | FASN (0.36) | KCNH2ADRA1DADRA1AADRA1BFASN | |
| SCHEMBL27475789 | 0.81 | SLC18A3 (0.43) | SIGMAR1KMT2A | |
| SCHEMBL11048064 | 0.78 | SLC18A3 (0.37) | KMT2AMRGPRX4 | |
| SCHEMBL7125778 | 0.77 | FASN (0.36) | KCNH2MRGPRX4FASN | |
| SCHEMBL3267939 | 0.76 | CETP (0.43) | KMT2A | |
| SCHEMBL27841792 | 0.75 | CETP (0.44) | KMT2A | |
| SCHEMBL27822714 | 0.75 | CETP (0.44) | KMT2A | |
| SCHEMBL9649306 | 0.74 | TSHR (0.39) | GRIA1GRIA2GRIA3KCNH2PGR | |
| SCHEMBL9649297 | 0.74 | TSHR (0.39) | GRIA1GRIA2GRIA3KCNH2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5172256-A | Liquid crystal variable color density lens and eye protective devices incorporating the same | LIQUID CRYSTAL OPTICS INSTITUTE, INC. | 1992-12-15 | — | — | US | claimed |
| US-4323472-A | ELECTROOPTICAL DISPLAY | TIMEX CORPORATION (US) | 1982-04-06 | — | — | US | claimed |