Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912623 | 0.84 | TSHR (0.47) | LMNATSHRTHRBDNM1 | |
| SCHEMBL1201252 | 0.84 | TSHR (0.47) | LMNATSHRTHRBDNM1 | |
| SCHEMBL3673386 | 0.73 | TSHR (0.40) | LMNATSHRTHRBDNM1 | |
| SCHEMBL180874 | 0.73 | TSHR (0.40) | LMNATSHRTHRBDNM1 | |
| SCHEMBL78510 | 0.73 | TSHR (0.40) | LMNATSHRTHRBDNM1 | |
| SCHEMBL3671630 | 0.73 | TSHR (0.40) | LMNATSHRTHRBDNM1 | |
| SCHEMBL80551 | 0.73 | TSHR (0.40) | LMNATSHRTHRBDNM1 | |
| SCHEMBL31235447 | 0.72 | DNM1 (0.36) | TSHRTHRBMAPTDNM1 | |
| SCHEMBL27507309 | 0.71 | TSHR (0.38) | LMNATSHRTHRBDNM1 | |
| SCHEMBL818787 | 0.71 | TSHR (0.38) | LMNATSHRTHRBDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157008-A | Reacting trimethylaluminum and trialkylaluminum with water or hydrates in hydrocarbon solvent yields alumoxanes having mixed alkyl groups and improved solubility | ETHYL CORPORATION (US) | 1992-10-20 | — | — | US | disclosed |