Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719724 | 1.00 | NPSR1 (0.41) | NPSR1ALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL13468240 | 0.76 | ALDH1A1 (0.47) | NPSR1ALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL7951918 | 0.75 | HCAR2 (0.44) | ALDH1A1KMT2AMEN1HCAR2GAA | |
| SCHEMBL7951921 | 0.75 | HCAR2 (0.44) | ALDH1A1KMT2AMEN1HCAR2GAA | |
| SCHEMBL6526076 | 0.75 | ALDH1A1 (0.50) | NPSR1ALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL13468225 | 0.75 | ALDH1A1 (0.50) | NPSR1ALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL6474807 | 0.75 | NPSR1 (0.44) | NPSR1ALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL6474803 | 0.75 | NPSR1 (0.44) | NPSR1ALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL6526079 | 0.75 | ALDH1A1 (0.50) | NPSR1ALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL5611998 | 0.73 | NPSR1 (0.52) | NPSR1ALDH1A1KMT2AMEN1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173502-A | For treating depression, hypertension, parkinson*s disease, asthma, convulasions, platelet aggregation of metabolic disorders | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |