Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 8/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719903 | 1.00 | BPTF (0.35) | BPTFPTAFRABCB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9719921 | 0.89 | POLB (0.39) | PTAFRABCB1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9719922 | 0.89 | POLB (0.39) | PTAFRABCB1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9719870 | 0.81 | PTAFR (0.48) | BPTFPTAFRABCB1 | |
| SCHEMBL9719869 | 0.81 | PTAFR (0.48) | BPTFPTAFRABCB1 | |
| SCHEMBL9719894 | 0.76 | PTAFR (0.37) | PTAFRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9719914 | 0.74 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL9719911 | 0.74 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL9719053 | 0.73 | PTAFR (0.43) | PTAFRALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL9719045 | 0.73 | PTAFR (0.43) | PTAFRALDH1A1SMN1; SMN2KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132463-A | Cardiovascular, skin, kidney, respiratory system, and gastrointestinal disorders | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| US-5047420-A | Platelet activating factor | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |