Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15943069 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL1783331 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL1783542 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL16786175 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL237372 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL16360132 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL16090836 | 0.83 | CA1 (0.47) | CA1 | |
| SCHEMBL1262390 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNASLC15A2 | |
| SCHEMBL1412935 | 0.82 | — | — | |
| SCHEMBL2348233 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TDP1LMNASLC15A2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104503-A | Radiation in presence of group 2b metal | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |