Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730742 | 0.89 | LMNA (0.60) | LMNATHRB | |
| Ether SCHEMBL3439244 | 0.83 | LMNA (0.41) | LMNATHRB | |
| Ether SCHEMBL7256702 | 0.83 | LMNA (0.41) | LMNATHRB | |
| SCHEMBL18775406 | 0.83 | LMNA (0.41) | LMNATHRBALDH1A1 | |
| Ether SCHEMBL491351 | 0.80 | LMNA (0.80) | LMNATHRBALDH1A1 | |
| SCHEMBL28639339 | 0.80 | LMNA (0.50) | LMNATHRB | |
| Ether SCHEMBL11433738 | 0.80 | LMNA (0.50) | LMNATHRBALDH1A1 | |
| Ether SCHEMBL7738174 | 0.78 | LMNA (0.44) | LMNATHRBALDH1A1 | |
| SCHEMBL7738082 | 0.78 | — | — | |
| SCHEMBL13409663 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104503-A | Radiation in presence of group 2b metal | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |