Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891741 | 0.91 | TSHR (0.37) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL1052850 | 0.88 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL1657137 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL1658306 | 0.88 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL26118 | 0.87 | — | — | |
| SCHEMBL16786319 | 0.87 | — | — | |
| SCHEMBL19501042 | 0.87 | — | — | |
| SCHEMBL811727 | 0.86 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL6003917 | 0.84 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL8532460 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104503-A | Radiation in presence of group 2b metal | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |