Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylbutanoic Acid SCHEMBL11314542 | 0.85 | LMNA (0.50) | LMNAALOX15HSD17B10SLC22A6TSHR | |
| SCHEMBL304303 | 0.84 | SLC22A6 (0.50) | LMNASLC22A6TSHRTDP1CACNA2D1 | |
| SCHEMBL5077944 | 0.84 | SLC22A6 (0.50) | LMNASLC22A6TSHRTDP1CACNA2D1 | |
| SCHEMBL6077847 | 0.78 | SLC22A6 (0.36) | SLC22A6TSHRTDP1CACNA2D1CACNB3 | |
| Acrylic Acid SCHEMBL5841577 | 0.78 | LMNA (0.71) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL17159430 | 0.78 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL29019793 | 0.78 | LMNA (0.42) | LMNAALOX15HSD17B10SLC22A6TSHR | |
| SCHEMBL13537824 | 0.78 | ABCC4 (0.38) | SLC22A6TSHRTDP1CACNA2D1CACNB3 | |
| SCHEMBL22500938 | 0.78 | ABCC4 (0.38) | SLC22A6TSHRTDP1CACNA2D1CACNB3 | |
| SCHEMBL9576393 | 0.78 | SLC22A6 (0.37) | LMNASLC22A6TDP1CACNA2D1CACNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104503-A | Radiation in presence of group 2b metal | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |