SCHEMBL9720402

SCHEMBL9720402

ClCc1c(Cl)cccc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.58
ALDH1A1 P00352 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 1/20 0.43
NPY1R P25929 1/20 0.43
NPY2R P49146 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
AKR1B1 P15121 1/20 0.41
MAOB P27338 2/20 0.39
CSNK2A1 P68400 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
MAPK14 Q16539 1/20 0.38
DPP4 P27487 3/20 0.38
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
HSD11B1 P28845 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10988341 0.82 CYP2A6 (0.56) CYP2A6ALDH1A1L3MBTL1LMNANPY1R
SCHEMBL5282536 0.82 CYP2A6 (0.56) CYP2A6ALDH1A1L3MBTL1LMNANPY1R
SCHEMBL27856687 0.82 CYP2A6 (0.56) CYP2A6ALDH1A1L3MBTL1LMNANPY1R
SCHEMBL28396527 0.80 CYP2A6 (0.54) CYP2A6ALDH1A1L3MBTL1LMNANPY1R
SCHEMBL31097818 0.80 CYP2A6 (0.54) CYP2A6ALDH1A1L3MBTL1LMNANPY1R
SCHEMBL736615 0.79 DPP4 (0.47) CYP2A6ALDH1A1L3MBTL1DPP4PDCD1
SCHEMBL11565506 0.78 PDCD1 (0.44) CYP2A6ALDH1A1SMN1; SMN2DPP4PDCD1
SCHEMBL15106903 0.77 CYP2A6 (0.50) CYP2A6ALDH1A1L3MBTL1LMNANPY1R
SCHEMBL31464089 0.77 CYP2A6 (0.50) CYP2A6ALDH1A1L3MBTL1LMNANPY1R
SCHEMBL11002642 0.77 CYP2A6 (0.50) CYP2A6ALDH1A1L3MBTL1LMNANPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114896-A Reaction product of magnesium, halogenated hydrocarbon, alkoxy compound, titanium compound, halogen-containing alcohol and solid halogenated hydrocarbon TONEN CORPORATION (JP) 1992-05-19 US disclosed
EP-0440813-A1 METHOD OF PRODUCING CATALYST COMPONENT FOR OLEFIN POLYMERIZATION Tonen Corporation (JP) 1991-08-14 EP disclosed