Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604835 | 0.76 | — | — | |
| SCHEMBL5604290 | 0.74 | — | — | |
| SCHEMBL9720562 | 0.74 | — | — | |
| SCHEMBL9720444 | 0.72 | KDM4E (0.33) | KDM4E | |
| SCHEMBL312626 | 0.71 | — | — | |
| SCHEMBL9720448 | 0.71 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6984577 | 0.68 | IRAK4 (0.47) | ALDH1A1 | |
| SCHEMBL9720449 | 0.68 | CCR4 (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL4781536 | 0.67 | MEN1 (0.39) | — | |
| SCHEMBL73851 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5075319-A | Bactericides | STERLING DRUG INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0417669-A2 | Pyridinyl-quinolone compounds, their preparation and use | STERLING WINTHROP INC. (US) | 1991-03-20 | — | — | EP | disclosed |