Styrene

Styrene

SCHEMBL9720511

C=Cc1ccccc1.CC=CC1CO1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
HDAC8 Q9BY41 2/20 0.32
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
JAK2 O60674 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
KDM1A O60341 3/20 0.31
CYP2C19 P33261 3/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP1A2 P05177 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1034343 0.79 ALDH1A1 (0.61) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL4794568 0.77 ALDH1A1 (0.64) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL6889906 0.76 ALDH1A1 (0.78) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL138531 0.73 ALDH1A1 (0.82) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL6837424 0.73 ALDH1A1 (0.82) ALDH1A1TSHRTDP1TP53HDAC8
SCHEMBL464833 0.73
SCHEMBL13309494 0.73
Styrene SCHEMBL11229860 0.73 TSHR (0.52) ALDH1A1TSHRTDP1TP53HDAC8
SCHEMBL202960 0.72 MAPT (0.51) ALDH1A1MAPTMEN1JAK2LMNA
SCHEMBL15184843 0.72 MAPT (0.51) ALDH1A1MAPTMEN1JAK2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096965-A POLYMERIC COMPOSITIONS SHELL OIL COMPANY (US) 1992-03-17 US disclosed