Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257193 | 0.87 | CYP3A4 (0.48) | CYP3A4TSHRALDH1A1HSD17B10NPC1 | |
| SCHEMBL29362146 | 0.85 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| SCHEMBL27474785 | 0.85 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| SCHEMBL16371573 | 0.85 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| SCHEMBL15174 | 0.85 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| SCHEMBL11394440 | 0.84 | CYP3A4 (0.96) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| SCHEMBL11394446 | 0.84 | CYP3A4 (0.96) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| Ethylene SCHEMBL11883084 | 0.84 | CYP3A4 (0.96) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| Phosphine SCHEMBL28202216 | 0.84 | CYP3A4 (0.96) | CYP3A4TSHRALDH1A1HSD17B10RHOA | |
| Methane SCHEMBL28309787 | 0.84 | CYP3A4 (0.96) | CYP3A4TSHRALDH1A1HSD17B10RHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128381-A | Polyetherurethane copolymers, high hysteresis loss, small compression set, flexibility | ACHILLES CORPORATION (JP) | 1992-07-07 | — | — | US | claimed |