SCHEMBL9720823

SCHEMBL9720823

Cc1c[c]c2ccccc2c1.Cc1c[c]c2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 8/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 7/20 0.40
NQO2 P16083 3/20 0.35
ALDH1A1 P00352 3/20 0.32
ACHE P22303 3/20 0.32
GLA P06280 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 2/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458019 1.00 CYP2A6 (0.44) CYP2A6TDP1CYP1A2NQO2ALDH1A1
SCHEMBL2698723 0.83 CYP2A6 (0.46) CYP2A6TDP1CYP1A2NQO2ALDH1A1
SCHEMBL666751 0.79 CYP2A6 (0.48) CYP2A6TDP1CYP1A2NQO2ALDH1A1
SCHEMBL667864 0.77 CYP1A2 (0.52) CYP2A6TDP1CYP1A2NQO2ALDH1A1
SCHEMBL2314445 0.76 MAPT (0.35) CYP2A6NQO2ALDH1A1ACHEGLA
SCHEMBL456729 0.74 CYP2A6 (0.46) CYP2A6CYP1A2NQO2ALDH1A1ACHE
SCHEMBL18317648 0.74 CYP2A6 (0.44) CYP2A6TDP1CYP1A2ALDH1A1MAPT
SCHEMBL457801 0.73 CYP2A6 (0.44) CYP2A6CYP1A2NQO2ALDH1A1ACHE
SCHEMBL458135 0.73 CYP2A6 (0.44) CYP2A6TDP1NQO2ALDH1A1ACHE
SCHEMBL75079 0.73 ALDH1A1 (0.44) CYP2A6TDP1NQO2ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171880-A Sulfur or oxidized sulfur in a base ALLIED-SIGNAL INC. (US) 1992-12-15 US disclosed
US-5171891-A Using sulfur containing oxy acids and their salts ALLIED-SIGNAL INC. (US) 1992-12-15 US disclosed