Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.73 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.60 |
| ▸ | CCKBR | P32239 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | MLNR | O43193 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720803 | 0.96 | NR1I2 (0.67) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL9720826 | 0.89 | NR1I2 (0.79) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL5437850 | 0.86 | CYP11B1 (0.80) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL5320974 | 0.86 | CYP11B1 (0.80) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL332630 | 0.85 | CYP11B1 (1.00) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL5290299 | 0.85 | CYP11B1 (0.73) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL5445913 | 0.85 | CYP11B1 (0.73) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| Hydrochloric Acid SCHEMBL5287102 | 0.84 | CYP11B1 (0.71) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL8184195 | 0.82 | CYP11B1 (0.73) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL7159462 | 0.82 | CYP11B1 (0.73) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149707-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1H-IMIDAZOLE USEFUL AS ANTIFUNGAL AGENT | J. URIACH & CIA, S.A. (ES) | 1992-09-22 | — | — | US | disclosed |
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | disclosed |