Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.80 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.78 |
| ▸ | CCKBR | P32239 | 2/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.78 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.78 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.78 |
| ▸ | MLNR | O43193 | 1/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320974 | 1.00 | CYP11B1 (0.80) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL9720803 | 0.91 | NR1I2 (0.67) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL332630 | 0.89 | CYP11B1 (1.00) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| Flutrimazole SCHEMBL29374184 | 0.88 | NR1I2 (1.00) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| Flutrimazole SCHEMBL154962 | 0.88 | NR1I2 (1.00) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL9720834 | 0.86 | CYP11B1 (0.73) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL5321882 | 0.85 | NR1I2 (0.60) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL11684935 | 0.85 | NR1I2 (0.63) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| SCHEMBL12199510 | 0.84 | CYP11B1 (0.89) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R | |
| Formaldehyde SCHEMBL27502810 | 0.84 | CYP11B1 (0.89) | CYP11B1CYP11B2NR1I2ADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037800-A1 | Method of treating neurological disorders using clotrimazole and derivatives thereof | ENVIVO PHARMACEUTICALS, INC. | 2007-02-15 | — | — | US | disclosed |
| US-3934022-A | N-trityl-imidazoles as plant fungicides | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037800-A1 | Method of treating neurological disorders using clotrimazole and derivatives thereof | HTT, HYPK, GRIK3 | CYP11B1 224/4885CYP11B2 175/4885NR1I2 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.