SCHEMBL9720843

SCHEMBL9720843

C=C(C)C(=O)OCCOC(=O)c1c(Br)c(Br)c(Br)c(Br)c1C(=O)OCCOC(=O)C(=C)C

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 4/20 0.44
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.36
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10717061 0.94 THRB (0.45) THRBTSHRCA1CA2POLB
SCHEMBL10406679 0.84 THRB (0.43) THRBTSHRCA1CA2
SCHEMBL10406211 0.84 THRB (0.43) THRBTSHRCA1CA2
SCHEMBL10903352 0.80 TSHR (0.47) THRBTSHRALDH1A1
SCHEMBL10627798 0.79 THRB (0.36) THRBTSHRALDH1A1
SCHEMBL9719502 0.79 THRB (0.55) THRBTSHRCA1CA2POLB
SCHEMBL15636 0.78 THRB (0.74) THRBTSHRCA1CA2POLB
SCHEMBL6142874 0.78 THRB (0.74) THRBTSHRCA1CA2POLB
SCHEMBL28782642 0.76 THRB (0.47) THRBTSHRCA1CA2POLB
Ethylene SCHEMBL955493 0.76 THRB (0.71) THRBTSHRCA1CA2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4918152-A COPOLYMERIZATION WITH A MALEIMIDE AND POLYFUNCTIONAL MONOMER; SMALL BIREFRINGENCE, HIGH REFRACTIVE INDEX; HIGH SPEED SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-04-17 US claimed
EP-0295012-B1 PROCESS FOR THE PRODUCTION OF FORMED ARTICLE OF AROMATIC VINYL RESIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-08 EP disclosed
EP-0270709-B1 PROCESS FOR THE PRODUCTION OF VINYL POLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-02-06 EP disclosed
US-4918152-A COPOLYMERIZATION WITH A MALEIMIDE AND POLYFUNCTIONAL MONOMER; SMALL BIREFRINGENCE, HIGH REFRACTIVE INDEX; HIGH SPEED SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-04-17 US disclosed
EP-0295012-A2 Process for the production of formed article of aromatic vinyl resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-12-14 EP disclosed
US-4783491-A SUBSTITUTED BROMINE HYDROCARBON AROMATIC METHACRYLATES; POLYMERIZABLE SANKIN KOGYO KABUSHIKI KAISHA (JP) 1988-11-08 US disclosed
EP-0270709-A1 Process for the production of vinyl polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-15 EP disclosed
US-4704006-A HIGH REFRACTIVE INDEX, DYEABILITY, SOLVENT RESISTANCE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-11-03 US disclosed
EP-0142921-B1 HALOGEN-CONTAINING RESIN LENS MATERIAL KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-08-26 EP disclosed