SCHEMBL9720867

SCHEMBL9720867

BrC1CCCC(Br)C(Br)C(Br)C(Br)C1Br

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190252 0.92 ALDH1A1 (0.39) KDM4EALDH1A1CYP3A4MAPTALOX15
SCHEMBL7097592 0.92 ALDH1A1 (0.39) KDM4EALDH1A1CYP3A4MAPTALOX15
SCHEMBL2404943 0.89 ALDH1A1 (0.36) KDM4EALDH1A1CYP3A4MAPTALOX15
SCHEMBL25670 0.89 ALDH1A1 (0.36) KDM4EALDH1A1CYP3A4MAPTALOX15
SCHEMBL3041394 0.89 ALDH1A1 (0.36) KDM4EALDH1A1CYP3A4MAPTALOX15
SCHEMBL94908 0.88 ALDH1A1 (0.33) KDM4EALDH1A1CYP3A4MAPTALOX15
SCHEMBL6264940 0.88
SCHEMBL6267036 0.85 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL3630820 0.84 KDM4E (0.46) KDM4EALDH1A1CYP3A4MAPTALOX15
SCHEMBL18107411 0.80 ALDH1A1 (0.33) KDM4EALDH1A1CYP3A4MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5116898-A Halogenated hydrocarbon, halogenated diphenyl ether ETHYL CORPORATION (US) 1992-05-26 US disclosed