Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | GHSR | Q92847 | 1/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720704 | 0.85 | OPRD1 (0.69) | KCNH2LMNANR1I2ADORA3CNR1 | |
| SCHEMBL9720683 | 0.85 | ATM (0.54) | KCNH2LMNANR1I2ADORA3CNR1 | |
| SCHEMBL9881223 | 0.83 | OPRD1 (1.00) | KCNH2LMNANR1I2ADORA3CNR1 | |
| Buclizine SCHEMBL22171621 | 0.83 | KCNH2 (1.00) | KCNH2LMNANR1I2ADORA3CNR1 | |
| Buclizine SCHEMBL27855 | 0.83 | KCNH2 (1.00) | KCNH2LMNANR1I2ADORA3CNR1 | |
| Buclizine SCHEMBL123752 | 0.83 | KCNH2 (1.00) | KCNH2LMNANR1I2ADORA3CNR1 | |
| SCHEMBL9720705 | 0.83 | KCNH2 (0.62) | KCNH2LMNANR1I2ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL2194307 | 0.82 | OPRD1 (0.98) | KCNH2LMNANR1I2ADORA3CNR1 | |
| Buclizine SCHEMBL123753 | 0.82 | KCNH2 (0.98) | KCNH2LMNANR1I2ADORA3CNR1 | |
| Buclizine SCHEMBL123751 | 0.82 | KCNH2 (0.98) | KCNH2LMNANR1I2ADORA3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |