Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3333138 | 0.89 | PIK3CD (0.40) | PIK3CDDRD2HTR7HTR1AHTR2C | |
| SCHEMBL12208456 | 0.79 | PIK3CD (0.38) | PIK3CDMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL15549868 | 0.77 | PIK3CD (0.36) | PIK3CDMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL15548788 | 0.72 | TSHR (0.39) | PIK3CDMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL84388 | 0.71 | GSK3A (0.35) | PTGS1GSK3AGSK3B | |
| SCHEMBL9720830 | 0.69 | PTGS1 (0.56) | PIK3CDMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL9720746 | 0.69 | PTGS1 (0.56) | PIK3CDMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL9720744 | 0.69 | PTGS1 (0.56) | PIK3CDMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL9752550 | 0.68 | TOP2A (0.47) | DRD2HTR7HTR1AHTR2CHRH1 | |
| SCHEMBL1101974 | 0.68 | MC4R (0.53) | MEN1LMNAKMT2AALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000740-A2 | BIS-DIOXOPIPERAZINES AND THEIR USE AS PROTECTION AGENTS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-01-23 | — | — | WO | disclosed |