Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720925 | 1.00 | MEN1 (0.42) | MEN1KMT2ATRPA1HPGDSMN1; SMN2 | |
| (Z)-1,2-Diphenylethene SCHEMBL29269291 | 0.95 | MAPK1 (0.44) | MEN1KMT2ATRPA1HPGDSMN1; SMN2 | |
| SCHEMBL10648311 | 0.93 | KDM4E (0.36) | MEN1KMT2ATRPA1HPGDSMN1; SMN2 | |
| SCHEMBL10648278 | 0.93 | KDM4E (0.36) | MEN1KMT2ATRPA1HPGDSMN1; SMN2 | |
| SCHEMBL12989702 | 0.83 | AKT1 (0.48) | MEN1KMT2ASMN1; SMN2MAPK1RELA | |
| SCHEMBL9868 | 0.82 | AKT1 (0.46) | MEN1KMT2AHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL11697638 | 0.82 | PTPN1 (0.41) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL11697648 | 0.82 | PTPN1 (0.41) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10648567 | 0.81 | MEN1 (0.50) | MEN1KMT2ATRPA1HPGDSMN1; SMN2 | |
| SCHEMBL28531472 | 0.81 | AKT1 (0.45) | MEN1KMT2AHPGDSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0252009-B1 | 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | claimed |
| EP-0252009-A1 | 1,4-Distyryl benzene compounds and their mixtures with other 1,4-distyryl benzene compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | claimed |
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0252009-B1 | 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | disclosed |
| EP-0252009-A1 | 1,4-Distyryl benzene compounds and their mixtures with other 1,4-distyryl benzene compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |
| US-4323675-A | Novel stilbene compounds: process for their manufacture and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |