Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 5/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648311 | 1.00 | KDM4E (0.36) | KDM4ECYP1A2MAPTCYP3A4CYP2C9 | |
| SCHEMBL9720925 | 0.93 | MEN1 (0.42) | KDM4ECYP1A2MAPTMAPK1HPGD | |
| SCHEMBL9720929 | 0.93 | MEN1 (0.42) | KDM4ECYP1A2MAPTMAPK1HPGD | |
| SCHEMBL13078874 | 0.87 | METAP2 (0.32) | SMN1; SMN2NPC1RAB9AMETAP2 | |
| SCHEMBL11697638 | 0.85 | PTPN1 (0.41) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11697648 | 0.85 | PTPN1 (0.41) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4233606 | 0.84 | DRD1 (0.38) | KDM4EMAPTALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11800913 | 0.83 | ESR1 (0.47) | KDM4EMAPTCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL11800928 | 0.83 | ESR1 (0.47) | KDM4EMAPTCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL16492294 | 0.82 | GLA (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136259-B1 | 4-HETEROCYCLYL-VINYL-4'-STYRYL-BIPHENYLS | CIBA-GEIGY AG (CH) | 1988-06-15 | — | — | EP | claimed |
| EP-0045279-B1 | AMINE OXIDE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | claimed |
| US-4666627-A | FLUORESCENT BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1987-05-19 | — | — | US | claimed |
| EP-0054511-B1 | 4-STYRYL-4'-VINYLBIFENYLS, METHODS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL WHITENERS | CIBA-GEIGY AG (CH) | 1987-05-13 | — | — | EP | claimed |
| EP-0136259-A1 | 4-Heterocyclyl-vinyl-4'-styryl-biphenyls | CIBA-GEIGY AG (CH) | 1985-04-03 | — | — | EP | claimed |
| US-4508784-A | 4-Styryl-4'-vinylbiphenyls, the production thereof and use thereof as fluorescent | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | claimed |
| EP-0054511-A2 | 4-Styryl-4'-vinylbifenyls, methods for their preparation and their use as optical whiteners | CIBA-GEIGY AG (CH) | 1982-06-23 | — | — | EP | claimed |
| EP-0136259-B1 | 4-HETEROCYCLYL-VINYL-4'-STYRYL-BIPHENYLS | CIBA-GEIGY AG (CH) | 1988-06-15 | — | — | EP | disclosed |
| US-4666627-A | FLUORESCENT BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1987-05-19 | — | — | US | disclosed |
| US-4539161-A | OPTICAL BRIGHTNERS, FLUORESCENT DYES | CIBA-GEIGY CORPORATION (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0136259-A1 | 4-Heterocyclyl-vinyl-4'-styryl-biphenyls | CIBA-GEIGY AG (CH) | 1985-04-03 | — | — | EP | disclosed |
| US-4508784-A | 4-Styryl-4'-vinylbiphenyls, the production thereof and use thereof as fluorescent | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| EP-0054511-A2 | 4-Styryl-4'-vinylbifenyls, methods for their preparation and their use as optical whiteners | CIBA-GEIGY AG (CH) | 1982-06-23 | — | — | EP | disclosed |