SCHEMBL9722182

SCHEMBL9722182

CC=Cc1ccc(OCc2ccc(COc3ccc(C=CC)cc3OC)cc2)c(OC)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.62
ALDH1A1 P00352 6/20 0.61
MAPT P10636 6/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
HPGD P15428 3/20 0.61
LMNA P02545 3/20 0.61
HTT P42858 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
NPSR1 Q6W5P4 1/20 0.61
ATM Q13315 1/20 0.59
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
MAPK1 P28482 1/20 0.57
MEN1 O00255 1/20 0.57
NFKB1 P19838 1/20 0.57
NFKB2 Q00653 1/20 0.57
KMT2A Q03164 1/20 0.57
RELA Q04206 1/20 0.57
PDCD1 Q15116 1/20 0.57
CD274 Q9NZQ7 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473709 1.00 POLB (0.62) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL14763980 0.92 APP (0.65) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL873590 0.92 APP (0.65) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL3271115 0.92 APP (0.65) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL891624 0.92 APP (0.65) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL29529587 0.92 APP (0.65) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL17629509 0.89 APP (0.61) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL15963939 0.86 APP (0.58) POLBALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL19734612 0.84 APP (0.70) ALDH1A1SMN1; SMN2HPGDHTTMEN1
SCHEMBL891274 0.83 ALDH1A1 (0.69) POLBALDH1A1MAPTSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5095074-A (Poly)bismaleimide and ther derivative of alkenylphenol HERCULES INCORPORATED (US) 1992-03-10 US disclosed
US-4962161-A BISMALEIMIDE OR POLYMALEIMIDE AND ETHER DERIVATIVE OF ALKENYLPHENOL HERCULES INCORPORATED (US) 1990-10-09 US disclosed
EP-0304009-A1 Thermosettable resin compositions HERCULES INCORPORATED (US) 1989-02-22 EP disclosed