Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.88 |
| ▸ | MAPT | P10636 | 1/20 | 0.88 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | SORD | Q00796 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzisothiazole-3-Yl-Piperazine SCHEMBL250876 | 0.95 | KDM4E (0.97) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL29432928 | 0.95 | KDM4E (0.97) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL7996950 | 0.94 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL9208072 | 0.94 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL9207008 | 0.94 | KDM4E (0.94) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL30204416 | 0.94 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL1737330 | 0.94 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL19733087 | 0.94 | KDM4E (0.94) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL4685549 | 0.87 | KDM4E (0.81) | KDM4EMAPTSORDHTR1ADRD2 | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL4209245 | 0.86 | KDM4E (0.79) | KDM4EMAPTSORDHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |