Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.97 |
| ▸ | MAPT | P10636 | 1/20 | 0.97 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | SORD | Q00796 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzisothiazole-3-Yl-Piperazine SCHEMBL29432928 | 1.00 | KDM4E (0.97) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL9207008 | 0.98 | KDM4E (0.94) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL19733087 | 0.98 | KDM4E (0.94) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL9208072 | 0.98 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL30204416 | 0.98 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL1737330 | 0.98 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL7996950 | 0.98 | KDM4E (1.00) | KDM4EMAPTHTR2CSORDHTR1A | |
| SCHEMBL9722339 | 0.95 | KDM4E (0.88) | KDM4EMAPTHTR2CSORDHTR1A | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL4685549 | 0.91 | KDM4E (0.81) | KDM4EMAPTSORDHTR1ADRD2 | |
| Benzisothiazole-3-Yl-Piperazine SCHEMBL3665521 | 0.90 | KDM4E (0.79) | KDM4EMAPTSORDHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4575806-B1 | COMPUTER SYSTEM AND PROCESS FOR PERFORMING RANDOM ACCESS OF A BIT IN A MEMORY | ST MICROELECTRONICS INT NV (CH) | 2026-05-13 | — | — | EP | claimed |
| CN-122011028-A | Method for efficiently preparing various substituted chiral phosphoramides | 上海交通大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4575806-A1 | COMPUTER SYSTEM AND PROCESS FOR PERFORMING RANDOM ACCESS OF A BIT IN A MEMORY | STMicroelectronics International N.V. (CH) | 2025-06-25 | — | — | EP | claimed |
| CN-119931086-A | MOF material for negative carbon hydrogen production and preparation and application methods thereof | 常州大学 | 2025-05-06 | — | — | CN | claimed |
| CN-116102524-B | Asymmetric synthesis method of beta-amino alcohol compound | 华东理工大学 | 2024-10-01 | — | — | CN | claimed |
| US-20230072612-A1 | FLAME RETARDANT CHEMICAL COMPOSITIONS | NORDTREAT FINLAND OY (FI) | 2023-03-09 | — | — | US | claimed |
| EP-4097176-A1 | FLAME RETARDANT CHEMICAL COMPOSITIONS | Nordtreat Finland OY (FI) | 2022-12-07 | — | — | EP | claimed |
| CN-115087697-A | Flame retardant chemical composition | 诺德特利特芬兰公司 | 2022-09-20 | — | — | CN | claimed |
| US-11292968-B2 | Sulfenamides as flame retardants | SONGWON INTERNATIONAL AG (CH) | 2022-04-05 | — | — | US | claimed |
| CN-114237552-A | Random sequence generation method, device, equipment and storage medium | 深圳忆联信息系统有限公司 | 2022-03-25 | — | — | CN | claimed |
| US-5861511-A | Process for preparation of 3 piperazinylbenzisothiazoles | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-19 | — | — | US | claimed |
| US-5856504-A | TREATING A 2-(ALKYLTHIO)BENZALDEHYDE OXIME WITH A HALOGEN COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| US-5756806-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-05-26 | — | — | US | claimed |
| EP-0835866-A1 | Process for preparation of 3-piperazinylbenzisothiazoles | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-04-15 | — | — | EP | claimed |
| EP-0805151-A1 | PROCESSES FOR PRODUCING ISOTHIAZOLE DERIVATIVES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-11-05 | — | — | EP | claimed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | claimed |
| EP-0623616-A1 | Heterocyclic compounds and process for the preparation thereof | EGIS GYOGYSZERGYAR RT. (HU) | 1994-11-09 | — | — | EP | claimed |
| EP-0364091-B1 | ANTIPSYCHOTIC 4-(4-(3-BENZISOTHIAZOLYL)-1-PIPERAZINYL)BUTYL BRIDGED BICYCLIC IMIDES | PFIZER INC. (US) | 1993-07-28 | — | — | EP | claimed |
| EP-0364091-A1 | Antipsychotic 4-(4-(3-benzisothiazolyl)-1-piperazinyl)butyl bridged bicyclic imides | PFIZER INC. (US) | 1990-04-18 | — | — | EP | claimed |
| US-4452799-A | NEUROLEPTIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1984-06-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292968-B2 | Sulfenamides as flame retardants | STS, TST, PFAS | KDM4E 870/4885MAPT 1238/4885HTR2C 2664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.