Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249844 | 0.88 | PDE10A (0.50) | DPP4NSD3CYP17A1CYP1A2PDE10A | |
| SCHEMBL12970144 | 0.85 | HSD11B1 (0.45) | DPP4AKT1NR1H4HSD11B1CYP17A1 | |
| SCHEMBL27249454 | 0.82 | CYP17A1 (0.47) | DPP4CYP17A1CYP1A2PDE10AALDH1A1 | |
| SCHEMBL12969932 | 0.82 | DPP4 (0.46) | DPP4AKT1NR1H4CYP17A1CYP1A2 | |
| SCHEMBL27249842 | 0.81 | CYP17A1 (0.43) | DPP4CYP17A1CYP1A2DDB1CRBN | |
| SCHEMBL12970089 | 0.80 | DPP4 (0.41) | DPP4AKT1NR1H4CYP17A1CYP1A2 | |
| SCHEMBL25478930 | 0.79 | HTT (0.55) | NR1H4CYP17A1ALDH1A1 | |
| SCHEMBL31221221 | 0.77 | NR1H4 (0.50) | NR1H4CYP17A1CYP1A2DHODH | |
| SCHEMBL23579933 | 0.77 | DPP4 (0.54) | DPP4AKT1NSD3DPP8CYP1A2 | |
| SCHEMBL12970435 | 0.76 | DPP4 (0.40) | DPP4NR1H4CYP17A1CYP1A2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140055-A | Improved high speed grip performance | BRIDGESTONE CORPORATION (JP) | 1992-08-18 | — | — | US | disclosed |
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |