SCHEMBL9722657

SCHEMBL9722657

O=CC1CCCCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.43
TSHR P16473 2/20 0.43
BLM P54132 1/20 0.41
EPHX1 P07099 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CAMK2A Q9UQM7 1/20 0.41
PRCP P42785 1/20 0.40
RET P07949 1/20 0.40
HTR2A P28223 1/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 2/20 0.39
CHRNA7 P36544 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8699708 0.94 IDO1 (0.49) IDO1TSHRBLMEPHX1CYP1A2
SCHEMBL29663637 0.94 IDO1 (0.49) IDO1TSHRBLMEPHX1CYP1A2
SCHEMBL9159890 0.94 IDO1 (0.49) IDO1TSHRBLMEPHX1CYP1A2
SCHEMBL782544 0.94 IDO1 (0.49) IDO1TSHRBLMEPHX1CYP1A2
SCHEMBL9165650 0.86 IDO1 (0.46) IDO1RETHTR2A
SCHEMBL21937667 0.86 IDO1 (0.46) IDO1RETHTR2A
SCHEMBL384149 0.86 IDO1 (0.46) IDO1RETHTR2A
Fluoride SCHEMBL29683041 0.85 IDO1 (0.44) IDO1RETHTR2A
SCHEMBL1567118 0.76 IDO1 (0.49) IDO1CYP2D6PRCPHTTALDH1A1
SCHEMBL6723016 0.76 IDO1 (0.49) IDO1CYP2D6HTTALDH1A1CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110989-A Pre- and postemergence; plant growth regulators ICI AUSTRALIA LIMITED (AU) 1992-05-05 US disclosed
US-4952722-A CYCLOHEX-2-EN-1-ONE DERIVATIVES; HERBICIDES ICI AUSTRALIA LIMITED (AU) 1990-08-28 US disclosed
EP-0086588-B1 CYCLOHEXANEDIONE DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM ICI AUSTRALIA LIMITED (AU) 1987-07-01 EP disclosed