Fluoride

Fluoride

SCHEMBL29683041

F.O=CC1CCc2ccccc21

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.44
PDPK1 O15530 1/20 0.44
RET P07949 1/20 0.42
HTR2A P28223 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CYP11B2 P19099 2/20 0.42
CYP17A1 P05093 1/20 0.41
CYP19A1 P11511 1/20 0.41
PIN1 Q13526 2/20 0.40
ACP3 P15309 1/20 0.40
SRD5A1 P18405 2/20 0.39
HTR6 P50406 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21937667 0.98 IDO1 (0.46) IDO1PDPK1RETHTR2ACA1
SCHEMBL9165650 0.98 IDO1 (0.46) IDO1PDPK1RETHTR2ACA1
SCHEMBL384149 0.98 IDO1 (0.46) IDO1PDPK1RETHTR2ACA1
Trimethylammonium SCHEMBL27680479 0.91 SIGMAR1 (0.45) IDO1PDPK1CA1CA2PIN1
SCHEMBL782544 0.86 IDO1 (0.49) IDO1RETHTR2A
SCHEMBL8699708 0.86 IDO1 (0.49) IDO1RETHTR2A
SCHEMBL9159890 0.86 IDO1 (0.49) IDO1RETHTR2A
SCHEMBL29663637 0.86 IDO1 (0.49) IDO1RETHTR2A
SCHEMBL9722657 0.85 IDO1 (0.43) IDO1RETHTR2A
SCHEMBL1567129 0.78 HTR1A (0.47) IDO1PDPK1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110536880-B Process for producing indanecarbaldehyde 三菱瓦斯化学株式会社 2022-07-05 CN disclosed