SCHEMBL9722738

SCHEMBL9722738

CC(Cl)S(=O)(=O)c1ccc2nc(N)sc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
HSD17B10 Q99714 3/20 0.66
HPGD P15428 2/20 0.66
LMNA P02545 2/20 0.66
PKM P14618 2/20 0.66
KDM4E B2RXH2 1/20 0.66
KMT2A Q03164 1/20 0.66
SMN1; SMN2 Q16637 3/20 0.54
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
SCN4A P35499 1/20 0.54
MAPT P10636 3/20 0.53
GFER P55789 2/20 0.53
VDR P11473 1/20 0.53
GPR55 Q9Y2T6 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP3A4 P08684 5/20 0.52
HTT P42858 2/20 0.51
USP2 O75604 1/20 0.51
CYP2C19 P33261 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9722715 0.86 ALDH1A1 (0.66) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL9722842 0.82 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL464726 0.80 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL686784 0.80 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL8298594 0.80 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL9722814 0.79 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL11592496 0.79 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL687982 0.79 ALDH1A1 (0.78) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL9722734 0.78 ALDH1A1 (0.71) ALDH1A1HSD17B10HPGDLMNAPKM
SCHEMBL1498187 0.77 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120872-A Textile dyeing CIBA-GEIGY CORPORATION (US) 1992-06-09 US disclosed
US-4994563-A Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness CIBA-GEIGY CORPORATION (US) 1991-02-19 US disclosed