SCHEMBL9722749

SCHEMBL9722749

CS(=O)(=O)c1ccc2nsc(N)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.41
IDE P14735 1/20 0.41
ILK Q13418 1/20 0.39
DHFR P00374 2/20 0.39
RIPK2 O43353 3/20 0.36
KDR P35968 2/20 0.36
NPBWR1 P48145 1/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
RET P07949 1/20 0.36
MAPK14 Q16539 1/20 0.36
PKMYT1 Q99640 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PIK3CD O00329 1/20 0.35
PIK3CA P42336 1/20 0.35
PIK3CB P42338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20748370 0.85 CA1 (0.42) ALDH1A1HPGDKMT2AMEN1RAB9A
SCHEMBL8063590 0.83 ALDH1A1 (0.46) ALDH1A1HPGDKMT2AMEN1KDM4E
SCHEMBL11698042 0.76 MAPK10 (0.36) KDM4EHSD17B10
SCHEMBL11684189 0.76 PRKD3 (0.47) KDRPIK3CB
SCHEMBL9722741 0.73 MAPT (0.43) NPC1RAB9ASMN1; SMN2KDM4ELMNA
SCHEMBL22650227 0.70 MAPT (0.47) ILKALDH1A1PIK3CGPKMHSD17B10
SCHEMBL2588818 0.70 NR4A2 (0.53) G6PDIDEDHFRRIPK2KDR
SCHEMBL14089193 0.69 MEN1 (0.51) G6PDIDENPBWR1ALDH1A1HPGD
SCHEMBL9722778 0.69 CYP1A2 (0.47) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL11699496 0.68 JAK2 (0.60) ILKRIPK2KDRLRRK2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120872-A Textile dyeing CIBA-GEIGY CORPORATION (US) 1992-06-09 US disclosed
US-4994563-A Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness CIBA-GEIGY CORPORATION (US) 1991-02-19 US disclosed
EP-0349486-A2 Azo dyes, their preparation and their use CIBA-GEIGY AG (CH) 1990-01-03 EP disclosed
US-4234482-A Substituted 3-carbalkoxy 4-alkylamino-azobenzene compound as disperse dyestuffs for synthetic fibers PRODUITS CHIMIQUES UGINE KUHLMANN SERVICE PROPRIETE INDUSTRIELLE (FR) 1980-11-18 US disclosed
US-4001203-A Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component CIBA-GEIGY AG (CH) 1977-01-04 US disclosed