Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722823 | 0.84 | ALDH1A1 (0.53) | CYP3A4TDP1ALDH1A1PDPK1GAA | |
| SCHEMBL2793048 | 0.84 | ALDH1A1 (0.49) | CYP3A4TDP1ALDH1A1PDPK1GAA | |
| SCHEMBL12109867 | 0.83 | MAPT (0.50) | ALDH1A1GAAMAPK1LMNAHSD17B10 | |
| SCHEMBL1936413 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL4470820 | 0.81 | PDPK1 (0.59) | CYP3A4TDP1ALDH1A1PDPK1SMN1; SMN2 | |
| SCHEMBL5670201 | 0.81 | PDPK1 (0.59) | CYP3A4TDP1ALDH1A1PDPK1GAA | |
| SCHEMBL6477475 | 0.81 | ALDH1A1 (0.45) | CYP3A4TDP1ALDH1A1PDPK1GAA | |
| Bromide SCHEMBL5669202 | 0.80 | PDPK1 (0.57) | CYP3A4TDP1ALDH1A1PDPK1GAA | |
| SCHEMBL9619834 | 0.78 | HSD17B10 (0.55) | CYP3A4ALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL6057635 | 0.77 | NSD1 (0.55) | CYP3A4TDP1ALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |