SCHEMBL9722816

SCHEMBL9722816

[CH]1Cc2cccc(-c3ccccc3)c2C1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.49
HTR1A P08908 4/20 0.42
HTR7 P34969 4/20 0.42
ANPEP P15144 2/20 0.41
IL1RN P18510 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
PARP10 Q53GL7 1/20 0.41
PARP11 Q9NR21 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9463233 0.76 PRCP (0.53) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL5346333 0.74 PRCP (0.61) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL30698218 0.74 PRCP (0.61) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL29401802 0.72 PNMT (0.53) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL27684703 0.72 ANPEP (0.50) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL70992 0.72 PNMT (0.53) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL29809707 0.72 PNMT (0.53) PRCPHTR1AHTR7ANPEPIL1RN
Bromide SCHEMBL15404509 0.71 PNMT (0.52) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL21401875 0.71 PRCP (0.58) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL11023731 0.71 PRCP (0.58) PRCPHTR1AHTR7ANPEPIL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0215701-B1 ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS AND 2,3-DIHYDRO-4-PHENYL-1H-INDEN-2-OL, THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1990-04-25 EP claimed
EP-0118873-B1 ACARICIDAL DIFLUOROETHENYLCYCLOPROPANECARBOXYLATES FMC Corporation (US) 1986-06-18 EP claimed
US-H49-H Process for producing 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylates FMC CORPORATION (US) 1986-04-01 US claimed
EP-0118873-A1 Acaricidal difluoroethenylcyclopropanecarboxylates FMC Corporation (US) 1984-09-19 EP claimed
US-5116826-A SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
US-5002957-A Insecticides, acaricides, nematocides HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-26 US disclosed
US-4990621-A Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
US-4966902-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-30 US disclosed
EP-0249015-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
EP-0224024-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-20 EP disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0085095-A1 INTERMEDIATES AND PROCESS FOR INSECTICIDAL SYNTHETIC PYRETHROIDS FMC Corporation (US) 1983-08-10 EP disclosed
EP-0069761-A4 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. FMC CORP (US) 1983-05-16 EP disclosed
WO-1983000485-A1 INTERMEDIATES AND PROCESS FOR INSECTICIDAL SYNTHETIC PYRETHROIDS FMC CORP (US) 1983-02-17 WO disclosed
EP-0069761-A1 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. FMC CORP (US) 1983-01-19 EP disclosed
WO-1982002321-A1 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES FMC CORP (US) 1982-07-22 WO disclosed
US-4335252-A A4-PHENYL-Z-INDANYL CYCLOPROPANE CARBOXYLATE FMC CORPORATION (US) 1982-06-15 US disclosed
US-4333950-A MITICIDES FMC CORPORATION (US) 1982-06-08 US disclosed
US-4250326-A Method of reducing the contents of haloethynyl-containing impurities in synthetic dihaloethenyl pyrethroid insecticides or intermediates by reaction with phosphites FMC CORPORATION (US) 1981-02-10 US disclosed