Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | FHIT | P49789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722770 | 0.78 | ALDH1A1 (0.33) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL12963136 | 0.75 | GAA (0.69) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL11441054 | 0.74 | KDM4E (0.51) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL17900475 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL28748179 | 0.70 | GAA (0.41) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL23413493 | 0.70 | GAA (0.56) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL28786633 | 0.70 | USP10 (0.56) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL11637070 | 0.70 | MAPT (0.59) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL38152 | 0.69 | MAPT (0.60) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL14234474 | 0.69 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |