SCHEMBL9722844

SCHEMBL9722844

N#CCCS(=O)(=O)c1ccc2nc(N)sc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.63
ALDH1A1 P00352 5/20 0.61
HSD17B10 Q99714 3/20 0.61
HPGD P15428 2/20 0.61
LMNA P02545 2/20 0.61
KDM4E B2RXH2 1/20 0.61
PKM P14618 1/20 0.61
KMT2A Q03164 1/20 0.61
CYP2D6 P10635 1/20 0.60
CYP3A4 P08684 5/20 0.55
MAPT P10636 3/20 0.50
GFER P55789 2/20 0.50
CYP2C9 P11712 2/20 0.50
VDR P11473 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.45
HTT P42858 2/20 0.45
USP2 O75604 1/20 0.45
TSHR P16473 2/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9722719 0.82 ALDH1A1 (0.66) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL11591589 0.82 ALDH1A1 (0.66) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL9722739 0.82 ALDH1A1 (0.66) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL1785869 0.81 ALDH1A1 (0.64) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL1787337 0.81 ALDH1A1 (0.64) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL9722734 0.80 ALDH1A1 (0.71) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL8951843 0.78 ALDH1A1 (0.59) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL8298594 0.77 ALDH1A1 (1.00) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL687982 0.75 ALDH1A1 (0.78) CYP2C19ALDH1A1HSD17B10HPGDLMNA
SCHEMBL686784 0.74 ALDH1A1 (0.76) CYP2C19ALDH1A1HSD17B10HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120872-A Textile dyeing CIBA-GEIGY CORPORATION (US) 1992-06-09 US disclosed
US-4994563-A Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness CIBA-GEIGY CORPORATION (US) 1991-02-19 US disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed