Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299189 | 0.80 | TSHR (0.46) | MAPTALDH1A1GAATSHRAR | |
| SCHEMBL31718395 | 0.80 | TSHR (0.46) | MAPTALDH1A1GAATSHRAR | |
| SCHEMBL10393827 | 0.79 | AR (0.34) | MAPTALDH1A1GAATSHRAR | |
| SCHEMBL10392854 | 0.78 | AR (0.36) | MAPTALDH1A1GAATSHRAR | |
| SCHEMBL10393862 | 0.76 | MAPT (0.41) | MAPTALDH1A1GAATSHRAR | |
| SCHEMBL27337733 | 0.75 | MAPT (0.38) | MAPTALDH1A1GAALMNARAB9A | |
| SCHEMBL27159366 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL30311684 | 0.73 | TSHR (0.41) | MAPTALDH1A1GAATSHRAR | |
| SCHEMBL2326737 | 0.73 | TSHR (0.41) | MAPTALDH1A1GAATSHRAR | |
| SCHEMBL29520654 | 0.71 | CYP3A4 (0.46) | MAPTALDH1A1TSHRLMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108595-A | Rehydroxylating with water and hydrogen fluoride or a basic activator | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| US-5032266-A | Chromatography | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-16 | — | — | US | disclosed |
| US-4874518-A | CHROMATOGRAPHY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |