SCHEMBL9723243

SCHEMBL9723243

C=CCn1c(=O)n(CCC[Si](OCC)(OCC)OCC)c(=O)n(CCC[Si](OCC)(OCC)OCC)c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.48
NPSR1 Q6W5P4 2/20 0.44
ADORA2B P29275 4/20 0.38
ADORA2A P29274 3/20 0.37
PDE4A P27815 2/20 0.37
PDE4B Q07343 2/20 0.37
PDE4C Q08493 2/20 0.37
PDE4D Q08499 2/20 0.37
USP2 O75604 2/20 0.37
GAA P10253 2/20 0.36
MAPT P10636 2/20 0.36
FPR1 P21462 1/20 0.36
HSD17B10 Q99714 1/20 0.34
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10457248 1.00 CYP3A4 (0.48) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL15369263 0.93 CYP3A4 (0.42) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL15369262 0.93 CYP3A4 (0.42) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL12565256 0.88 TP53 (0.42) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL383223 0.87 RGS4 (0.32) ADORA2BADORA2APDE4APDE4BPDE4C
SCHEMBL15369261 0.87 CYP3A4 (0.39) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL17750827 0.87 CYP3A4 (0.47) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL15369225 0.85 CYP3A4 (0.46) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL1252938 0.84 CYP3A4 (0.52) CYP3A4NPSR1ADORA2BADORA2APDE4A
SCHEMBL1252609 0.84 CYP3A4 (0.52) CYP3A4NPSR1ADORA2BADORA2APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107429064-B Resin composition for electric/electronic component 迈图高新材料日本合同公司 2021-03-16 CN disclosed
WO-2020130072-A1 COATING AGENT, COATING FILM, AND LAMINATE DIC株式会社 2020-06-25 WO disclosed
EP-2657301-B1 ULTRAVIOLET-CURABLE SILICONE RESIN COMPOSITION AND IMAGE DISPLAY DEVICE USING SAME MOMENTIVE PERFORMANCE MAT JP (JP) 2015-03-11 EP disclosed
US-8716362-B2 Ultraviolet-curable silicone resin composition, and image display device using the same MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) 2014-05-06 US disclosed
EP-2657301-A1 ULTRAVIOLET-CURABLE SILICONE RESIN COMPOSITION AND IMAGE DISPLAY DEVICE USING SAME Momentive Performance Materials Japan LLC (JP) 2013-10-30 EP disclosed
US-20130065983-A1 ULTRAVIOLET-CURABLE SILICONE RESIN COMPOSITION, AND IMAGE DISPLAY DEVICE USING THE SAME MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) 2013-03-14 US disclosed
US-7879451-B2 Silicone rubber coating composition and airbag SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-02-01 US disclosed
US-20070100043-A1 Adhesive composition SHIN-ETSU CHEMICAL CO., LTD. 2007-05-03 US disclosed
US-5158988-A Containing photoinitiator; curable by visible light TOSHIBA SILICONE CO., LTD. (JP) 1992-10-27 US disclosed