Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883734 | 0.82 | KMT2A (0.56) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL13879115 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL1751092 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL9416789 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL2124402 | 0.78 | KMT2A (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL27003740 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL9416684 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL14546800 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL10681711 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL10334224 | 0.75 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |