Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9552935 | 0.94 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9552332 | 0.93 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL9552815 | 0.92 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9552070 | 0.92 | AGTR1 (0.40) | AGTR1AGTR2PPARG | |
| SCHEMBL9552624 | 0.91 | AGTR1 (0.41) | AGTR1PPARG | |
| SCHEMBL9738101 | 0.90 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9552384 | 0.89 | CNR2 (0.44) | AGTR1AGTR2PPARG | |
| SCHEMBL7335984 | 0.89 | AGTR1 (0.37) | AGTR1 | |
| SCHEMBL7341359 | 0.89 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL9552752 | 0.89 | AGTR1 (0.39) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140036-A | Hypotensive agents; congestive heart failure; angiotensin antagonists | G. D. SEARLE & CO. (US) | 1992-08-18 | — | — | US | disclosed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |