Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 5/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670030 | 0.93 | LPO (0.44) | LPO | |
| SCHEMBL972118 | 0.87 | LPO (0.55) | LPOLMNACYP1A2ALDH1A1KMT2A | |
| SCHEMBL22504083 | 0.87 | TLR8 (0.43) | LMNACYP1A2MAPTATMALDH1A1 | |
| Sulfuric Acid SCHEMBL7256482 | 0.76 | LPO (0.41) | LPOTYRLMNACYP1A2 | |
| SCHEMBL18686733 | 0.72 | TYR (0.41) | TYRCYP1A2ALDH1A1ADORA2AADORA2B | |
| SCHEMBL19411183 | 0.72 | LPO (0.35) | LPO | |
| SCHEMBL12122681 | 0.71 | LPO (0.46) | LPOLMNACYP1A2MAPTATM | |
| SCHEMBL9522704 | 0.69 | ESR1 (0.41) | LMNAMAPTATMALDH1A1KMT2A | |
| SCHEMBL257387 | 0.67 | — | — | |
| SCHEMBL21859332 | 0.67 | TYR (0.33) | LPOTYRLMNAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084542-A | Clear colorless resistant coatings with improved weatherability | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991018937-A1 | EPOXY/ISOCYANATE CROSSLINKED COATINGS CONTAINING 1,3-DISUBSTITUTED IMIDAZOLE-2-THIONE CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |