Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 9/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723418 | 1.00 | KCNH2 (0.56) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL8700052 | 0.88 | KCNH2 (0.52) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL8698523 | 0.88 | KCNH2 (0.52) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL17627701 | 0.86 | KCNH2 (0.55) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL1866120 | 0.86 | KCNH2 (0.55) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL11745664 | 0.86 | KCNH2 (0.55) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL9723550 | 0.86 | KCNH2 (0.55) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL4933865 | 0.86 | KCNH2 (0.55) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL17627703 | 0.86 | KCNH2 (0.55) | KCNH2TDP1KDM4ETSHRHTT | |
| SCHEMBL4097947 | 0.86 | KCNH2 (0.50) | KCNH2TDP1KDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175347-A | Hydogenation of a ester compound in presence of hydrogen using solid catalyst | KALI-CHEMIE PHARMA GMBH (DE) | 1992-12-29 | — | — | US | disclosed |