Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888803 | 0.97 | TSHR (0.61) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL24555351 | 0.95 | TSHR (0.59) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL8367937 | 0.95 | TSHR (0.59) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL4578978 | 0.93 | ESR1 (0.59) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL5694111 | 0.92 | TSHR (0.56) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL5694203 | 0.91 | TSHR (0.55) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL17034380 | 0.89 | TSHR (0.59) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL5694128 | 0.89 | ESR1 (0.54) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL12807612 | 0.89 | TSHR (0.56) | ESR1TSHRLMNACYP2D6SMN1; SMN2 | |
| SCHEMBL28027210 | 0.87 | TSHR (0.52) | ESR1TSHRLMNACYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4054150-A | — | — | None | — | — | JP | disclosed |
| WO-2015126666-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |
| US-7232644-B2 | Polymerizable composition and negative-working planographic printing plate precursor using the same | FUJIFILM CORPORATION (JP) | 2007-06-19 | — | — | US | disclosed |
| JP-H0454150-A | PRODUCTION OF 3-CHLORO-4-HYDROXYBENZOIC ACID DERIVATIVE HAVING POLYMERIZABLE GROUP | FUJI PHOTO FILM CO LTD | 1992-02-21 | — | — | JP | disclosed |