SCHEMBL28027210

SCHEMBL28027210

C=CC(=O)OCCCOC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
TDP1 Q9NUW8 2/20 0.51
HTT P42858 2/20 0.48
THRB P10828 1/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C19 P33261 2/20 0.45
ESR1 P03372 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPK1 P28482 1/20 0.45
NR1H2 P55055 1/20 0.45
RNASEL Q05823 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP2C9 P11712 1/20 0.44
PDE4D Q08499 1/20 0.44
TP53 P04637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22700833 0.97 TSHR (0.56) TSHRALDH1A1CYP3A4TDP1HTT
SCHEMBL4645535 0.93 THRB (0.54) TSHRALDH1A1CYP3A4TDP1HTT
SCHEMBL434675 0.89 TDP1 (0.68) TSHRALDH1A1CYP3A4TDP1THRB
SCHEMBL9723588 0.87 ESR1 (0.61) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL29315934 0.86 TDP1 (0.56) TSHRALDH1A1CYP3A4TDP1THRB
SCHEMBL4645538 0.86 TSHR (0.57) TSHRALDH1A1CYP3A4TDP1THRB
SCHEMBL36483 0.86 TDP1 (0.67) TSHRALDH1A1CYP3A4TDP1HTT
SCHEMBL222350 0.86 HTT (0.65) TSHRALDH1A1CYP3A4TDP1HTT
SCHEMBL14597318 0.86 TSHR (0.50) TSHRALDH1A1CYP3A4TDP1HPGD
SCHEMBL17036979 0.86 THRB (0.58) TSHRALDH1A1CYP3A4TDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104804382-B The preparation method of the filling-modified Poly(Trimethylene Terephthalate) of a kind of negative ion 福建师范大学泉港石化研究院 2016-06-15 CN claimed
CN-104804382-A Preparation method of negative ion filled and modified PTT (polytrimethylene terephthalate) QUANGANG PETROCHEMICAL RES INST FUJIAN NORMAL UNIV 2015-07-29 CN claimed
CN-104804382-B The preparation method of the filling-modified Poly(Trimethylene Terephthalate) of a kind of negative ion 福建师范大学泉港石化研究院 2016-06-15 CN disclosed
CN-104804382-B The preparation method of the filling-modified Poly(Trimethylene Terephthalate) of a kind of negative ion 福建师范大学泉港石化研究院 2016-06-15 CN disclosed
CN-104804382-A Preparation method of negative ion filled and modified PTT (polytrimethylene terephthalate) QUANGANG PETROCHEMICAL RES INST FUJIAN NORMAL UNIV 2015-07-29 CN disclosed