Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27341360 | 0.95 | ALDH1A1 (0.71) | ALDH1A1TSHRTHRBMGAMGAA | |
| Propane SCHEMBL23527365 | 0.92 | ALDH1A1 (0.83) | ALDH1A1TSHRTHRBMGAMGAA | |
| Propane SCHEMBL6470806 | 0.92 | ALDH1A1 (0.83) | ALDH1A1TSHRTHRBMGAMGAA | |
| Propanol SCHEMBL9442818 | 0.90 | ALDH1A1 (0.71) | ALDH1A1TSHRTHRBMGAMGAA | |
| Ethylene Glycol SCHEMBL335787 | 0.90 | ALDH1A1 (0.79) | ALDH1A1TSHRTHRBMGAMGAA | |
| Butane SCHEMBL7941631 | 0.90 | ALDH1A1 (0.79) | ALDH1A1TSHRTHRBMGAMGAA | |
| Ethylene Glycol SCHEMBL704710 | 0.90 | ALDH1A1 (0.79) | ALDH1A1TSHRTHRBMGAMGAA | |
| SCHEMBL1849 | 0.89 | — | — | |
| SCHEMBL10636466 | 0.89 | — | — | |
| SCHEMBL4390490 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250724-B | Polyurethane sole and preparation method thereof | 温州市巨伦鞋业有限公司 | 2020-09-22 | — | — | CN | claimed |
| US-20240148741-A1 | FORMULATION FOR ORAL ADMINISTRATION, COMPRISING TRIAZINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| CN-108250724-B | Polyurethane sole and preparation method thereof | 温州市巨伦鞋业有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-106256762-B | preparation method of multilayer graphene | 光州科学技术院 | 2019-06-21 | — | — | CN | disclosed |
| CN-108867150-A | A kind of modified methacrylic acid methyl esters insulating paper | 天长市富柏特电子有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-102766020-B | Method for producing ethanol, acetone and butanol by permeabilization, vaporization, coupling and rectification of ABE (Acetone, Butanol and Ethanol) fermentation liquor | UNIV BEIJING CHEMICAL | 2014-11-05 | — | — | CN | disclosed |
| CN-102766020-A | Method for producing ethanol, acetone and butanol by permeabilization, vaporization, coupling and rectification of ABE (Acetone, Butanol and Ethanol) fermentation liquor | UNIV BEIJING CHEMICAL | 2012-11-07 | — | — | CN | disclosed |
| CN-1685586-A | magnetic rotor for motor | MITSUBISHI ELECTRIC CORP (JP) | 2005-10-19 | — | — | CN | disclosed |
| US-5136005-A | Composition and method of preparation of solid state dye laser rods | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1992-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148741-A1 | FORMULATION FOR ORAL ADMINISTRATION, COMPRISING TRIAZINE DERIVATIVE | MKI67, IL5, IL15 | ALDH1A1 3279/4885TSHR 1138/4885THRB 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.