Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777436 | 0.73 | HPGD (0.42) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL3345476 | 0.73 | HPGD (0.44) | KMT2AHPGDMYCALDH1A1L3MBTL1 | |
| SCHEMBL7949878 | 0.72 | HPGD (0.47) | SMN1; SMN2KMT2AHPGDMYCALDH1A1 | |
| SCHEMBL13379131 | 0.72 | KMT2A (0.54) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5096830 | 0.71 | HPGD (0.46) | SMN1; SMN2KMT2AHPGDMYCERCC5 | |
| SCHEMBL29645048 | 0.71 | CES1 (0.50) | SMN1; SMN2HPGDMYCALDH1A1ERCC5 | |
| SCHEMBL8914360 | 0.71 | HPGD (0.46) | SMN1; SMN2HPGDMYCALDH1A1L3MBTL1 | |
| SCHEMBL19278858 | 0.71 | HPGD (0.46) | SMN1; SMN2KMT2AHPGDMYCALDH1A1 | |
| SCHEMBL1199962 | 0.71 | CES1 (0.50) | SMN1; SMN2HPGDMYCALDH1A1ERCC5 | |
| SCHEMBL8844053 | 0.71 | AKT1 (0.50) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169958-A | Reacting, 3-amino-2-propen-1-ones with magnesium halide in solvent | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |