Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723836 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723707 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723739 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723726 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723817 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723754 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723861 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723858 | 1.00 | ABCC4 (0.38) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723811 | 0.99 | ABCC4 (0.36) | ABCC4MAPTALDH1A1LMNACYP3A4 | |
| SCHEMBL9723768 | 0.95 | FAAH (0.33) | ABCC4MAPTKMT2AFAAHCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368933-B1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0368933-A1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1990-05-23 | — | — | EP | disclosed |