Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265791 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNARXFP1ATM | |
| SCHEMBL9269846 | 0.74 | MEN1 (0.42) | KMT2AMEN1 | |
| SCHEMBL9723936 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNARXFP1ATM | |
| SCHEMBL8188082 | 0.67 | RXFP1 (0.39) | ALDH1A1KDM4ERXFP1TSHRMAPT | |
| SCHEMBL9271308 | 0.66 | MAPT (0.61) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL705208 | 0.64 | MAPT (0.68) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL9265847 | 0.63 | MEN1 (0.47) | KMT2AMAPTMEN1RAB9ANPC1 | |
| SCHEMBL29280508 | 0.63 | PPARG (0.54) | ALDH1A1KDM4ELMNARXFP1TSHR | |
| SCHEMBL16689961 | 0.62 | KMT2A (0.67) | ALDH1A1KDM4ELMNAESR2TSHR | |
| SCHEMBL1988247 | 0.62 | TSHR (0.68) | ALDH1A1KDM4ELMNAESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |